Oral Inverted Ductal Papilloma: Report of a Case with Immunohistochemical Study

Oral inverted ductal papilloma (IDP) is a very uncommon lesion of minor salivary gland origin. Forty five cases have been reported in the literature. We describe a case of IDP developed as an asymptomatic submucosal mass in the hard palate of a middle-aged woman. Excisional biopsy was performed, and ten months of patient’s follow-up showed no evidence of recurrence. The major portion of the tumour was made up of proliferating configurations containing epidermoid cells. Some microcysts and crypts were seen. Immunohistochemical analysis of the present case supports the hypothesis that IDP arises from excretory duct cells.